[Comparative study of the effectiveness of inactivated influenza vaccine preparations]

The reactogenicity, safety, immunogenicity and epidemiological effectiveness of inactivated virion vaccinal preparations from strains A (H3N2) Texas 1/77a, A (H1N1) and split adsorbed influenza chemical vaccine, as well as the character of local and systemic reactions to these vaccines were studied. The vaccinees showed a high percentage of seroconversions (42-69.4%) with antibody titers increasing 5 times and more. At the period of the epidemic outbreak of influenza in January 1980, caused by influenza virus A (H3N2) Texas 1/77a, morbidity rate among persons immunized with the vaccine homologous to the epidemic strain was 2.5 times lower than among nonimmunized persons.