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Irradiated mandibular autografts.

R C Hamaker, M I Singer, W W Shockley

    Cancer
    |September 15, 1983
    PubMed
    Summary
    This summary is machine-generated.

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    This study presents a new method for reconstructing the jawbone after oral cancer surgery using irradiated mandibular autografts. This technique shows a 66% success rate with minimal morbidity, offering a viable option for patients with mandibular defects.

    Area of Science:

    • Oral oncology
    • Surgical reconstruction
    • Radiation oncology

    Background:

    • Mandibular resection for oral cancer causes significant cosmetic and functional disability.
    • Segmental resections are preferred but lead to deformities, often leading to less preferred marginal resections.
    • Postoperative radiation therapy is frequently used, complicating reconstruction.

    Purpose of the Study:

    • To evaluate the efficacy of primary reconstruction using irradiated mandibular autografts after oncologic resection.
    • To assess the success rate and morbidity associated with this reconstructive technique.

    Main Methods:

    • Fifteen patients with oral cavity cancer involving the mandible underwent resection.
    • Immediate reconstruction was performed using irradiated mandibular autografts.

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  • Patients received 10,000 rad of radiation therapy post-reconstruction.

    • Main Results:

    • The study followed patients for up to 4 years and 3 months.
    • A success rate of 66% was achieved with irradiated mandibular autografts.
    • Morbidity was minimal compared to traditional autogenous bone grafting.

    Conclusions:

    • Primary reconstruction with irradiated mandibular autografts is a feasible option for mandibular defects after oral cancer resection.
    • This method offers a low morbidity alternative to other reconstructive techniques.
    • Factors like tumor size, prior radiation, or flap use did not impact the success of this reconstruction.