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A new miniature, open-loop, extracorporeal insulin infusion pump
Journal of Biomedical Engineering
|July 1, 1983
Summary
This new extracorporeal insulin infuser offers a compact and user-friendly solution for diabetes management. It provides precise insulin delivery for both clinical studies and long-term treatment of insulin-dependent diabetes mellitus.
Area of Science:
- Biomedical Engineering
- Endocrinology
- Medical Devices
Background:
- Insulin-dependent diabetes mellitus (IDDM) requires continuous insulin management.
- Existing insulin delivery systems may lack convenience or long-term usability.
- Development of advanced insulin infusers is crucial for improving patient care.
Purpose of the Study:
- To introduce a novel extracorporeal insulin infuser designed for IDDM.
- To evaluate its suitability for clinical investigations and long-term patient treatment.
- To highlight its user-friendly design and extended operational capabilities.
Main Methods:
- Utilized an unconventionally designed syringe driver for insulin delivery.
- Incorporated electronic control for variable basal infusion rates.
- Enabled mealtime bolus infusions via pushbutton activation.
- Prefilled syringes with specially formulated standard-strength insulin for extended use.
Main Results:
- The device is compact and simple to operate.
- Insulin capacity supports at least one week of treatment without refilling.
- Features electronically controlled variable basal rates and pushbutton bolus doses.
- Audible signals indicate dose regimes, alarms, and system failures.
Conclusions:
- The developed insulin infuser is a viable option for IDDM clinical investigations and long-term management.
- Its design prioritizes user convenience, extended operational duration, and precise insulin delivery.
- The device facilitates subcutaneous insulin delivery, with potential for other administration routes.