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Summary
This review highlights the shift in periodontal therapy chemotherapeutics during the 1970s, focusing on topical antimicrobials like chlorhexidine for gingivitis and supragingival plaque. Future research in the 1980s will explore subgingival plaque and systemic antibiotics for periodontal disease.
Area of Science:
- Periodontology
- Microbiology
- Pharmacology
Background:
- The 1970s saw a focus on chemotherapeutic agents in periodontal therapy.
- Investigations into chlorhexidine spurred research into topical antimicrobials for gingivitis and supragingival plaque control.
Purpose of the Study:
- To review the chemotherapeutic aspects of periodontal therapy in the 1970s.
- To anticipate future trends in periodontal antimicrobial therapy for the 1980s.
Main Methods:
- Emphasis on the chemotherapeutic approaches used in the 1970s.
- Review of studies on topical antimicrobial agents, particularly chlorhexidine.
- Discussion of emerging trends for the 1980s, including subgingival plaque and systemic antibiotics.
Main Results:
- Topical antimicrobial agents, like chlorhexidine, were investigated for their effects on supragingival plaque and gingivitis during the 1970s.
- Anticipated focus in the 1980s includes subgingival plaque, innovative drug delivery into the gingival crevice, and systemic antibiotics.
Conclusions:
- Periodontal therapy chemotherapeutics evolved significantly in the 1970s, with a focus on topical agents.
- The 1980s are predicted to see advancements in targeting subgingival plaque and utilizing systemic antibiotics with improved efficacy and safety profiles for periodontal disease treatment.