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Mood, vegetative disturbance, and dexamethasone suppression test after stroke
Annals of Neurology
|November 1, 1982
Summary
Stroke patients show higher rates of mood and vegetative disturbances, with abnormal dexamethasone suppression tests (DST) linked to these symptoms. DST may aid in diagnosing and monitoring post-stroke mood changes.
Area of Science:
- Neurology
- Psychiatry
- Endocrinology
Background:
- Mood and vegetative disturbances are common after stroke.
- The dexamethasone suppression test (DST) is a potential biomarker for these disturbances.
Purpose of the Study:
- To assess the prevalence of mood and vegetative disturbances in stroke patients.
- To evaluate the utility of the DST in stroke patients.
Main Methods:
- A single-dose dexamethasone suppression test (DST) was administered to 25 stroke patients and 13 controls.
- Mood and vegetative disturbances were assessed using standardized measures.
Main Results:
- Stroke patients exhibited significantly higher rates of mood (48%) and vegetative (52%) disturbances compared to controls (0% and 8%).
- Abnormal DST results were more prevalent in stroke patients (52%) than controls (8%).
- Abnormal DST results correlated with mood, appetite, and sleep disturbances.
Conclusions:
- The DST may serve as a valuable tool for diagnosing and monitoring mood and vegetative disturbances post-stroke.
- These disturbances are potentially reversible and DST can track recovery.