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[Immunologic responses in the dynamics of the establishment of postvaccinal measles immunity]
Abstract:
The comparative study of the humoral and cellular characteristics of antimeasles immunity in children immunized with live measles vaccine Ji-16, and in children having had measles revealed that both "wild" and vaccine strains of measles virus induced similar changes in the organism of the child: the synthesis of specific antibodies belonging to different physico-chemical classes, changes in the content of different serum immunoglobulins and the suppression of the blastogenic response of peripheral blood lymphoyctes to phitohemagglutinins. The changes suggest that both T- and B-lymphocytes took part in the formation of antimeasles immunity, but all these processes were more pronounced during the formation of postinfection immunity.
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