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DNA Methylation: Bisulphite Modification and Analysis
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DNA Methylation: Bisulphite Modification and Analysis

Published on: October 21, 2011

Hybridization analysis of the methylated bases of Escherichia coli DNA

A Quint, H Cedar

    Biochimica Et Biophysica Acta
    |February 29, 1980
    PubMed

    Abstract:

    The 5-methylcytosine residues of Escherichia coli DNA are randomly dispersed along the genome. Hybridization data indicate that these methyl moieties are transcribed at the same frequency as the total DNA. These results suggest that DNA methylation probably does not play a role in gene expression in bacteria.

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