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Updated: Aug 15, 2026

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DNA Methylation: Bisulphite Modification and Analysis
Published on: October 21, 2011
Hybridization analysis of the methylated bases of Escherichia coli DNA
Biochimica Et Biophysica Acta
|February 29, 1980
Abstract:
The 5-methylcytosine residues of Escherichia coli DNA are randomly dispersed along the genome. Hybridization data indicate that these methyl moieties are transcribed at the same frequency as the total DNA. These results suggest that DNA methylation probably does not play a role in gene expression in bacteria.
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