[Gastric secretion of white rats in endotoxic shock]

The output of gastric secretion, gastric juice pH and its proteolytic activity are studied in twelve white rats in the state of endotoxic shock. Gastric juice from the animals is collected during two different periods - prior to shock, and during the shock - with the first period serving as a control. The proteolytic capacity of gastric juice is assayed enzymophoretically. In the course of endotoxin shock a statistically reliable decrease in gastric secretion output, as well as reduced acidity manifested with increase in pH and reduction to full disappearance of the proteolytic capacity of gastric juice are established in the animals experimented upon. The obtained results are interpreted in the light of direct and indirect inhibition of the gastric mucosa secretory activity.