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Permanent percutaneous devices

A F von Recum, J B Park

    Critical Reviews in Bioengineering
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Percutaneous devices (PDs) connect internal organs to external equipment but often fail due to skin interface breakdown. Understanding epidermal healing, biomaterial compatibility, and mechanical stress is key to improving PD longevity.

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    Area of Science:

    • Biomaterials Science
    • Tissue Engineering
    • Medical Device Design

    Background:

    • Percutaneous devices (PDs) are crucial for connecting internal body structures to external equipment.
    • Current PDs frequently fail due to breakdown at the skin interface shortly after implantation.
    • This limits their clinical utility and necessitates improved designs.

    Purpose of the Study:

    • To review the current understanding of percutaneous device-skin interface pathophysiology.
    • To identify key factors contributing to the failure of percutaneous devices.
    • To discuss ongoing research and clinical reports on permanent percutaneous devices.

    Main Methods:

    • Literature review of the pathophysiology of the PD-skin interface.
    • Analysis of epidermal healing peculiarities in relation to PDs.

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  • Evaluation of biomaterial compatibility and mechanical stress at the interface.

    • Main Results:

    • The PD-skin interface failure is a common mode for all current devices.
    • Factors contributing to failure include impaired epidermal healing, lack of biocompatible materials, and mechanical stresses.
    • These factors can act independently or in combination to cause device failure.

    Conclusions:

    • Improving percutaneous device longevity requires addressing the challenges of epidermal healing and biomaterial integration.
    • Further research into novel biomaterials and interface designs is essential.
    • Optimizing mechanical stability at the PD-skin interface is critical for long-term function.