Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Does pulsatile flow improve glucose tolerance during extracorporeal circulation

R W Landymore, D A Murphy, E Kinley

    The Journal of Cardiovascular Surgery
    |May 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Testing spatial working memory in pigs using an automated T-maze.

    Oxford open neuroscience·2024
    Same author

    A phase II open-label trial of avelumab plus axitinib in previously treated non-small-cell lung cancer or treatment-naïve, cisplatin-ineligible urothelial cancer.

    ESMO open·2023
    Same author

    Mechanical circulatory support is associated with loss of platelet receptors glycoprotein Ibα and glycoprotein VI.

    Journal of thrombosis and haemostasis : JTH·2016
    Same author

    Methamphetamine Users Have Increased Dental Disease: A Propensity Score Analysis.

    Journal of dental research·2016
    Same author

    Mitral valve repair in a Jehovah's witness with haemophilia A with high-titre inhibitor.

    Haemophilia : the official journal of the World Federation of Hemophilia·2015
    Same author

    Correlates of emotional distress among HIV+ youths: Health status, stress, and personal resources.

    Annals of behavioral medicine : a publication of the Society of Behavioral Medicine·2013
    Same journal

    Development of a new dedicated bridging stent for FEVAR: initial ideas, design and testing, on-label approval, and initial experience.

    The Journal of cardiovascular surgery·2026
    Same journal

    Pelvic venous disease and lymphatic dysfunction: evaluating the evidence for a proposed continuum.

    The Journal of cardiovascular surgery·2026
    Same journal

    Incidence of post-dissection aneurysmal formation and need for secondary intervention after surgery for acute type A aortic dissections: a systematic review and meta-analysis of observational studies.

    The Journal of cardiovascular surgery·2026
    Same journal

    The expertise effect: how advancing skills in frozen elephant trunk have broadened surgical indication for acute dissection.

    The Journal of cardiovascular surgery·2026
    Same journal

    Outcomes of pulmonary embolism response teams: a systematic review.

    The Journal of cardiovascular surgery·2026
    Same journal

    Use of large bore devices in the treatment of pulmonary embolism.

    The Journal of cardiovascular surgery·2026
    See all related articles

    Pulsatile flow during cardiac surgery did not affect glucose tolerance in patients. While systemic resistance was lower with pulsatile flow, both groups showed similar glucose levels and impaired insulin secretion during extracorporeal circulation.

    Area of Science:

    • Cardiovascular Surgery
    • Metabolic Physiology

    Background:

    • Cardiac surgery often requires cardiopulmonary bypass, altering physiological conditions.
    • The impact of different blood flow patterns during bypass on glucose metabolism is not fully understood.

    Purpose of the Study:

    • To investigate the effect of pulsatile versus non-pulsatile blood flow on glucose tolerance during cardiac surgery.
    • To assess systemic resistance and insulin secretion in relation to flow patterns.

    Main Methods:

    • A comparative study involving twenty cardiac surgery patients.
    • Patients were randomized into two groups: non-pulsatile bypass (n=10) and pulsatile flow bypass (n=10).
    • Systemic resistance, glucose tolerance, and insulin secretion were monitored.

    Related Experiment Videos

    Main Results:

    • Patients on pulsatile flow exhibited significantly lower systemic resistance in the intensive care unit.
    • Glucose tolerance was comparable between the pulsatile and non-pulsatile flow groups.
    • Both groups demonstrated impaired insulin secretion and elevated serum glucose during extracorporeal circulation.

    Conclusions:

    • Pulsatile blood flow during cardiac surgery does not appear to influence glucose tolerance.
    • Impaired insulin secretion and hyperglycemia are observed during extracorporeal circulation regardless of flow pattern.