[Effect of the fixation time on tumor mitotic regimen]

The mitotic regimen of 10 carcinomas from 8 patients was studied. The material was cut and fixed immediately, 1, 2, and 24 hours after the removal of the tumor. The intensity of changes in the mitotic regimen was shown to rise with the increasing length of the period from tumor removal to its fixation. This is likely to be due to partial retention of the capacity of the removed tumor cells to enter mitosis which leads to "accumulation" of dividing cells in the metaphase by the type of K-mitosis.