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[Pathomorphological changes in colibacteriosis in pigs]
Veterinarno-Meditsinski Nauki
|January 1, 1981
Summary
Colibacteriosis in piglets is a severe, generalized disease affecting multiple organs, including the brain. This Escherichia coli infection can lead to septicemia and toxemia in young pigs.
Area of Science:
- Veterinary Pathology
- Microbiology
- Animal Health
Background:
- Colibacteriosis, caused by Escherichia coli, is a significant disease in suckling piglets.
- Previous studies have focused on intestinal lesions, but systemic effects require further investigation.
Purpose of the Study:
- To investigate the morphological lesions associated with spontaneous and experimental colibacteriosis in suckling piglets.
- To determine the systemic impact of Escherichia coli infection on various organs in young pigs.
Main Methods:
- Morphological investigation of 46 spontaneously affected and 20 experimentally infected piglets (aged 1-10 days).
- Experimental infection using two strains of Escherichia coli: O149 and O138.
- Detailed examination of intestinal, visceral, and brain tissues.
Main Results:
- Severe lesions were observed in intestines, viscera, and brain in both spontaneous and experimental cases.
- Catarrhal to hemorrhagic enteritis, hepatic dystrophy, kidney lesions, and meningoencephalitis were prevalent.
- Bacterial thrombi were found in blood vessels, adrenals, and thymus in spontaneously affected piglets.
- Escherichia coli O149 induced more severe changes than O138.
Conclusions:
- Colibacteriosis in suckling pigs is a severe, generalized disease with systemic effects.
- The infection can manifest as septicemia and toxemia, impacting multiple organs beyond the intestines.
- Pathogenic E. coli strains can have a broader spectrum of action in young hosts.