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Related Experiment Videos

See-saw nystagmus

I M Williams, P Dickinson, R J Ramsay

    Australian Journal of Ophthalmology
    |February 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    See-saw ocular movements, a rare eye movement disorder, were observed in two patients. These disconjugate eye movements are linked to lesions affecting specific brain circuitry, resulting in irregular, alternating eye motions.

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    Area of Science:

    • Neuroscience
    • Ophthalmology
    • Neurology

    Background:

    • See-saw ocular movements are a rare conjugate or disconjugate nystagmus characterized by one eye moving upward while the other moves downward.
    • The exact pathophysiology remains incompletely understood, with proposed mechanisms involving brainstem and diencephalic structures.

    Observation:

    • Two patients presented with see-saw ocular movements: one with obstructive hydrocephalus and the other with a thalamic infarct.
    • Electro-oculography revealed irregular, alternating horizontal and vertical disconjugate eye movements, exaggerated in bright light and reduced during fixation.

    Findings:

    • The observed see-saw ocular movements suggest a lesion affecting the circuitry involving the nucleus centromedianus of the thalamus, zona incerta, interstitial nucleus of Cajal, and midbrain/pontine eye movement cells.

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  • The dynamic and ever-changing pattern of these disconjugate movements is attributed to the controlling influence of extensive brain connections.

    • Implications:

    • This study contributes to understanding the neural basis of see-saw ocular movements and associated neurological conditions.
    • Identifying the affected neural circuitry aids in diagnosing and potentially managing patients with these complex eye movement abnormalities.