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Related Experiment Videos

Recruitment from clinical studies

D B Hunninghake, F Peterson, M LaDouceur

    Circulation
    |December 1, 1982
    PubMed
    Summary

    Clinical study referrals offer an efficient recruitment strategy, yielding a high entry-to-contact ratio and low costs. Maximizing these referrals when available is crucial for successful clinical trial recruitment.

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    Area of Science:

    • Clinical Research
    • Trial Recruitment Strategies
    • Public Health Interventions

    Background:

    • Referrals from related clinical studies are a valuable recruitment source.
    • This source typically involves fewer initial contacts but a higher conversion rate.
    • Effort required from recruitment teams is generally lower.

    Purpose of the Study:

    • To evaluate the effectiveness and efficiency of clinical study referrals as a recruitment source.
    • To analyze the contribution of referrals to initial contacts, protocol visits, and final entries in a specific trial (CPPT).
    • To highlight successful recruitment campaign elements and cost-effectiveness.

    Main Methods:

    • Analysis of recruitment data from the CPPT, specifically tracking referrals from other clinical studies.
    • Identification of major contributing studies, such as the Multiple Risk Factor Intervention Trial and the Minnesota LRC.
    • Assessment of recruitment costs and efficiency ratios.

    Main Results:

    • Referrals constituted 1% of initial contacts, 9% of first protocol visits, and 11% of entries in the CPPT.
    • Two-thirds of referral entries originated from the Multiple Risk Factor Intervention Trial.
    • Recruitment costs associated with this strategy were typically low.

    Conclusions:

    • Clinical study referrals are an attractive recruitment strategy due to their high efficiency and low cost.
    • Maximizing the use of available clinical study referrals is recommended.
    • While not always consistently available, this source significantly benefits trial recruitment efforts.

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