Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Combined microwave therapy

A J Nelson, J A Holt

    The Medical Journal of Australia
    |July 29, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Advanced head and neck cancer treatment using radiowave hyperthermia combined with radiotherapy showed a 94% lesion resolution and 54% three-year survival. This innovative approach significantly outperformed conventional therapies.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The comparison of biphasic and monophasic waveforms through commercially available systems.

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
    Same author

    Practical recommendations for treating patients with chronic kidney disease in Australia: a multidisciplinary approach.

    Internal medicine journal·2026
    Same author

    Waveform matters: enhanced cortical plasticity with monophasic intermittent theta-burst stimulation.

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2026
    Same author

    Characterizing the neurophysiology of complex regional pain syndrome using transcranial magnetic stimulation.

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2025
    Same author

    Ipsilateral motor pathways related to proximal upper limb function in tetraplegia.

    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology·2025
    Same author

    The influence of menstrual phase on synaptic plasticity induced via intermittent theta-burst stimulation.

    Neuroscience·2024
    Same journal

    Responding to the Revised First Nations Health and Cultural Safety Accreditation Standards in Australian Primary Medical Education: Institutional Principles and Qualities for Meaningful Progress.

    The Medical journal of Australia·2026
    Same journal

    Multimorbidity Clusters Among People Aged 65 Years and Over in Australia: A Nationwide Cross-Sectional Data Linkage Study.

    The Medical journal of Australia·2026
    Same journal

    Reducing Nitrous Oxide Emissions Across the Melbourne Biomedical Precinct.

    The Medical journal of Australia·2026
    Same journal

    Still Treating Yesterday's Risk? Reconsidering Antiviral Use for Mild-to-Moderate COVID-19 Cases in a Broadly Immune Population.

    The Medical journal of Australia·2026
    Same journal

    Striving for Racial Equity in Oral Cancer Research: A Case Study.

    The Medical journal of Australia·2026
    Same journal

    Progressing Cross-Sector Collaboration for People With Eating Disorders and Higher Weight: Priority Actions From an Expert Roundtable Using a Modified Nominal Group Technique.

    The Medical journal of Australia·2026
    See all related articles

    Area of Science:

    • Oncology
    • Medical Physics
    • Radiotherapy

    Background:

    • Advanced head and neck cancer presents significant treatment challenges.
    • Conventional therapies like cobalt radiotherapy and supervoltage therapy have limited efficacy.
    • Hyperthermia offers a promising adjunct to radiation therapy.

    Purpose of the Study:

    • To evaluate the efficacy of 434-MHz radiowave hyperthermia combined with cobalt radiotherapy and/or radioactive gold grain implant for advanced head and neck cancer.
    • To compare the outcomes of this combined treatment with historical controls receiving hyperbaric oxygen and cobalt or conventional supervoltage therapy.

    Main Methods:

    • Fifty-two patients with advanced head and neck cancer were treated.
    • The primary treatment involved 434-MHz radiowave hyperthermia combined with cobalt radiotherapy and/or radioactive gold grain implant.

    Related Experiment Videos

  • Outcomes were compared to retrospective series using hyperbaric oxygen and cobalt or conventional supervoltage therapy.

    • Main Results:

    • Complete resolution of primary and secondary lesions was achieved in 94% of cases treated with radiowave hyperthermia.
    • The three-year survival rate for the radiowave hyperthermia group was 54%.
    • Comparable series showed lower resolution rates (62.5% and 36.5%) and three-year survival rates (29% and 19%) for hyperbaric oxygen and conventional supervoltage therapy, respectively.

    Conclusions:

    • 434-MHz radiowave hyperthermia combined with radiotherapy offers a highly effective treatment for advanced head and neck cancer.
    • This combined modality demonstrates superior outcomes in lesion resolution and patient survival compared to conventional treatments.
    • Radiowave hyperthermia represents a significant advancement in the management of advanced head and neck malignancies.