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The Lee Obesity Index vindicated?

E L Simson, R M Gold

    Physiology & Behavior
    |August 1, 1982
    PubMed
    Summary
    This summary is machine-generated.

    The Lee Obesity Index reliably predicts body fat in diet-induced obese rats, but is less accurate for ovariectomized or pellet-fed rats. Simpler measures may be equally effective for assessing body fat.

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    Area of Science:

    • Animal models
    • Obesity research
    • Body composition analysis

    Background:

    • Accurate assessment of body fat is crucial in obesity research.
    • The Lee Obesity Index is a commonly used tool for estimating adiposity in rodents.
    • Understanding the reliability of different obesity indices under various physiological conditions is important.

    Purpose of the Study:

    • To evaluate the correlation between the Lee Obesity Index and percent body fat in rats.
    • To determine the reliability of the Lee Obesity Index in different experimental groups, including diet-induced obesity, ovariectomy, and sham surgery.
    • To compare the predictive power of the Lee Obesity Index with simpler anthropometric measures.

    Main Methods:

    • Rats were divided into groups receiving either a supermarket diet or Lab Chow pellets, combined with ovariectomy or sham surgery, at weaning or as adults.

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  • Body composition was assessed using the Lee Obesity Index and carcass analysis (percent body fat).
  • Correlations were calculated between the Lee Obesity Index, percent body fat, body weight, and a weight/length ratio.

    • Main Results:

    • The Lee Obesity Index showed a strong correlation with percent body fat in rats made obese by diet.
    • The index was less reliable for ovariectomized rats and pellet-fed sham-operated controls.
    • Percent body fat also correlated well with body weight and a simple weight/length ratio in diet-induced obese rats.

    Conclusions:

    • The Lee Obesity Index can reliably predict percent body fat in diet-induced obese rats.
    • Its reliability is compromised in ovariectomized rats and some control groups.
    • Simpler measures like body weight and weight/length ratio may offer comparable accuracy for assessing body fat in specific contexts.