[Blood ammonia in mice bearing Ehrlich ascites tumors]

The NH4+ concentrations in plasma and ascitic liquid of mice bearing tumor were determined over the time of tumor growth. A significant ammonia increase in the host's blood was detected in 13-14th days after inoculations. NH4+ in the ascitic liquid rose to 0.63 mM. Preliminary results suggested that NH4+ found in ascitic liquid and in the host's blood was produced by tumor cells from glutamine.