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[Chronic hypervitaminosis A with skin changes]

K Hamann, C Avnstorp

Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

|October 1, 1982

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A woman experienced skin issues resembling contact dermatitis due to excessive vitamin A intake. Symptoms resolved after discontinuing high-dose vitamin A supplements.

Area of Science:

Dermatology
Toxicology
Nutritional Science

Background:

Hypervitaminosis A is a condition caused by excessive intake of vitamin A.
Dermatologic manifestations can be varied and sometimes mimic other skin conditions.
Long-term, high-dose supplementation poses a risk for toxicity.

Observation:

A 43-year-old woman presented with dermatologic symptoms.
Her dermatitis resembled contact dermatitis or pellagra.
She consumed 100,000 IU of vitamin A daily for 15 months, with 2-month intervals.

Findings:

The patient's dermatologic symptoms were solely due to hypervitaminosis A.
The observed dermatitis was a direct consequence of chronic vitamin A toxicity.
Gradual resolution of skin symptoms occurred after cessation of vitamin A intake.

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Implications:

This case highlights the importance of recognizing unusual dermatologic presentations of vitamin A toxicity.
It underscores the potential risks associated with self-prescribed, high-dose vitamin A supplementation.
Clinicians should consider vitamin A toxicity in patients with unexplained dermatitis, especially with a history of high intake.