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[Hematological and biochemical changes in lambs experimentally infested with Cysticercus ovis]
Veterinarno-Meditsinski Nauki
|January 1, 1982
Summary
Experimental Cysticercus ovis infection in lambs significantly altered hematological indices, notably increasing leukocyte counts, eosinophils, and lymphocytes while decreasing neutrophils. These changes were most pronounced between 7 and 35 days post-infection.
Area of Science:
- Veterinary Parasitology
- Animal Hematology
- Infectious Diseases
Background:
- Cysticercus ovis infection, caused by Taenia ovis larvae, poses a significant health concern in sheep.
- Understanding the hematological and biochemical impact of T. ovis infection is crucial for diagnosing and managing parasitic diseases in lambs.
Purpose of the Study:
- To investigate the hematological and biochemical effects of experimental Cysticercus ovis infection in lambs.
- To determine the correlation between infection dosage and observed physiological changes.
Main Methods:
- Fourteen two-month-old lambs were divided into three experimental groups (infected with 4000, 7000, or 30,000 T. ovis eggs) and one control group.
- Hematological and biochemical analyses were performed pre-infection and at multiple time points post-infection (days 4, 7, 12, 28, 35, and 60).
Main Results:
- Experimental infection with Cysticercus ovis led to a significant increase in total leukocyte count in infected lambs.
- Differential blood counts revealed a rise in eosinophils and lymphocytes, alongside a decrease in neutrophils.
- The observed hematological alterations were more pronounced in the period between 7 and 35 days post-infection across all infected groups.
Conclusions:
- Experimental Cysticercus ovis infection causes notable hematological changes in lambs, indicating an immune response.
- The study highlights specific alterations in leukocyte profiles as potential biomarkers for T. ovis infection in sheep.