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Related Experiment Videos

Hydrocephalic infants: developmental assessment and computed tomography

M G Thompson, H M Eisenberg, H S Levin

    Child'S Brain
    |January 1, 1982
    PubMed
    Summary
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    Infants with hydrocephalus and brain injury show lower cognitive scores. Ventricle-brain ratio (VBR) correlates with mental development, but VBR changes over time do not significantly alter cognitive scores in children with shunts.

    Area of Science:

    • Pediatric Neurology
    • Developmental Neuroscience

    Background:

    • Hydrocephalus is a condition characterized by excess cerebrospinal fluid in the brain.
    • Shunt placement is a common treatment for hydrocephalus in infants.
    • The impact of co-occurring brain injury on cognitive outcomes in infantile hydrocephalus requires further investigation.

    Purpose of the Study:

    • To investigate the relationship between hydrocephalus, co-existing brain injury, and cognitive development in infants.
    • To assess the correlation between ventricular dilatation and cognitive scores.
    • To evaluate changes in ventricular size and cognitive function over one year.

    Main Methods:

    • Studied 29 infants (under 30 months) with shunted hydrocephalus.
    • Utilized the Bayley Mental Scale for cognitive assessment.

    Related Experiment Videos

  • Computed the ventricle-brain ratio (VBR) from computed tomography (CT) scans.

    • Main Results:

    • Infants with hydrocephalus and brain injury had significantly lower Bayley Mental Scale scores compared to those with uncomplicated hydrocephalus.
    • A negative correlation was observed between VBR and Bayley Mental Scale scores.
    • After one year, VBR decreased significantly, but mental quotient remained unchanged in two-thirds of the sample.

    Conclusions:

    • Brain injury significantly impacts cognitive prognosis in hydrocephalic children.
    • Ventricle-brain ratio is an indicator of cognitive function in infants with hydrocephalus.
    • While ventricular size can change, cognitive outcomes may stabilize in the short term for shunted hydrocephalic infants.