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Updated: Aug 3, 2026

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Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
Published on: March 12, 2016
Comparing the mydriatic effect of tropicamide with respect to iris pigmentation
Abstract:
It has been believed over the years that mydriatics have had lesser effect on darker pigmented irides. In this study pupillary diameter was measured under 70 foot-candles of illumination before and after 1% tropicamide was instilled for a duration period of 30 minutes. It was concluded that, (a) 1% tropicamide did dilate the pupil, (b) light irides were significantly larger than dark irides before dilation, (c) no significant difference in the change of pupil size between light and dark irides was evidenced.
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