The pediatric spectrum of dynamic left ventricular obstruction

Twenty-one pediatric patients with echocardiographic and/or hemodynamic evidence of dynamic left ventricular obstruction are presented in order to examine the pathophysiologic mechanisms of this disorder. Neonates commonly had transient hypertrophic cardiomyopathy related to hypertension or to being infants of diabetic mothers. Infants with D-transposition of the great arteries sometimes developed signs of subpulmonic dynamic obstruction. Older children and adolescents had either classic findings of IHSS or concentric left ventricular hypertrophy. The spectrum of hypertrophic cardiomyopathy appears to be broader in pediatric patients than in adults.