Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cell processes in basal cell carcinoma

B Cutler, Z Posalaky, H I Katz

    Journal of Cutaneous Pathology
    |October 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Basal cell carcinoma exhibits three distinct cell process types within intercellular spaces. These processes, unlike those in squamous cell carcinoma, typically do not breach the tumor

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Comparing para-rowing set-ups on an ergometer using kinematic movement patterns of able-bodied rowers.

    Journal of sports sciences·2016
    Same author

    Randomized clinical trial of tranexamic acid-free fibrin sealant during vascular surgical procedures.

    The British journal of surgery·2010
    Same author

    Topical corticosteroids in psoriasis: strategies for improving safety.

    Journal of the European Academy of Dermatology and Venereology : JEADV·2010
    Same author

    Effect of a desogestrel-containing oral contraceptive on the skin.

    The European journal of contraception & reproductive health care : the official journal of the European Society of Contraception·2001
    Same author

    Therapeutic studies with a new combination benzoyl peroxide/clindamycin topical gel in acne vulgaris.

    Cutis·2001
    Same author

    A combination benzoyl peroxide and clindamycin topical gel compared with benzoyl peroxide, clindamycin phosphate, and vehicle in the treatment of acne vulgaris.

    Cutis·2001
    Same journal

    Blastic Plasmacytoid Dendritic Cell Neoplasm.

    Journal of cutaneous pathology·2026
    Same journal

    Atypical Grover Disease Associated With Merkel Cell Carcinoma: A Novel Paraneoplastic Presentation.

    Journal of cutaneous pathology·2026
    Same journal

    Profile of a Founder: Herbert Zachareus Lund.

    Journal of cutaneous pathology·2026
    Same journal

    The National Resident Match Program Arrives in Dermatopathology: 15 Years of Resilient Advocacy by the American Society of Dermatopathology's Fellowship Training Program Directors' Committee.

    Journal of cutaneous pathology·2026
    Same journal

    Evaluating Large Language Models for Melanocytic Lesion Pathology Report Interpretation.

    Journal of cutaneous pathology·2026
    Same journal

    An Atypical Skin Presentation of Adult-Onset Still's Disease With Histological Description: A Case Report.

    Journal of cutaneous pathology·2026
    See all related articles

    Area of Science:

    • Dermatopathology
    • Cell Biology

    Background:

    • Basal cell carcinoma (BCC) is the most common human cancer.
    • Understanding the ultrastructural features of BCC is crucial for differentiating it from other skin neoplasms.
    • Intercellular processes are a notable ultrastructural feature in some epithelial tumors.

    Purpose of the Study:

    • To describe and characterize the three distinct types of intercellular cell processes observed in basal cell carcinoma.
    • To compare the behavior of these processes in BCC with their behavior in squamous cell carcinoma.

    Main Methods:

    • Transmission electron microscopy was used to examine tissue samples from basal cell carcinoma.
    • Cellular processes within intercellular spaces were identified and categorized based on morphology.
    • The relationship of these processes to the basal lamina was assessed.

    Related Experiment Videos

    Main Results:

    • Three types of intercellular cell processes were identified in BCC: thin, microvilli-like processes; thick, mesa-like processes with desmosomes; and large, bulging processes.
    • These processes were more abundant in spinocellular cells compared to basaloid cells.
    • Crucially, BCC cell processes generally did not penetrate the basal lamina, unlike those in invasive squamous cell carcinoma.

    Conclusions:

    • The three identified cell process types represent characteristic ultrastructural features of basal cell carcinoma.
    • The limited penetration of the basal lamina by BCC cell processes distinguishes it from more invasive carcinomas, potentially reflecting differences in tumor behavior and invasiveness.