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Published on: February 18, 2015
Anti-pigment-cell factors and mucocutaneous candidiasis
Abstract:
Previous reports documented the fact that some patients with mucocutaneous candidiasis and vitiligo have a complement-fixing anti-pigment-cell factor in their serum. We examined sera from seven patients with mucocutaneous candidiasis without vitiligo. Three of the seven sera contained the anti-pigment-cell factor. We suggest that these anti-pigment-cell factors, which are most probably antibodies, are not cytotoxic for pigment cells and, thus, not the cause of vitiligo. The association of vitiligo and anti-pigment-cell factors with the syndrome of mucocutaneous candidiasis implicates the immune system are a causal factor of vitiligo.
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