[Dowling-Degos disease with involvement of the scalp]

Dowling-Degos disease is described in a 40 year-old man, involving the nape of the neck, axillary regions, scrotum, intergluteal fold and also the scalp. There was no associated hair growth anomaly. There was extensive pitting of the entire face. Dowling-Degos disease appears to result from a genetically determined imbalance of epithelial-mesenchymal regulatory mechanisms causing increased epithelial proliferation, as well as a disturbance of the maturation and differentiation of the proliferating keratinocytes.