Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tumor-specific antigens

M Pfreundschuh, H Shiku, T Takahashi

    Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer
    |January 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Hemostatic abnormalities in patients with thrombotic complications on maintenance hemodialysis.

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2000
    Same author

    Efficacy of a new formulation of lenograstim (recombinant glycosylated human granulocyte colony-stimulating factor) containing gelatin for the treatment of neutropenia after consolidation chemotherapy in patients with acute myeloid leukemia.

    International journal of hematology·2000
    Same author

    Effects of cyclosporin A on refractory B-cell chronic lymphocytic leukemia.

    International journal of hematology·2000
    Same author

    Aberrations of the tissue factor pathway in patients positive for lupus anticoagulant.

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2000
    Same author

    Outcome of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in Japan.

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2000
    Same author

    Increased activated protein C: protein C inhibitor complex and decreased protein C inhibitor levels in patients with chronic renal failure on maintenance hemodialysis.

    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis·2000
    Same journal

    Future Challenges of Molecular Imaging in Oncology.

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
    Same journal

    Clinical Applications of Theranostics.

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
    Same journal

    Internal Radiation Therapy.

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
    Same journal

    The Role of Molecular Imaging in Ion Beam Therapy.

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
    Same journal

    Molecular Imaging in Photon Radiotherapy.

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
    Same journal

    Advancements in Intraoperative Imaging for Enhanced Surgical Precision.

    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer·2026
    See all related articles

    Researchers identified three classes of surface antigens on astrocytoma cells using autologous sera. These findings aid in understanding tumor-specific markers and comparing them to other cancers.

    Area of Science:

    • Oncology
    • Immunology
    • Cell Biology

    Background:

    • Astrocytoma cells possess unique surface antigens.
    • Autologous serological typing is a method to identify these antigens.
    • Understanding tumor-specific markers is crucial for cancer research.

    Purpose of the Study:

    • To define classes of surface antigens on human astrocytoma cells.
    • To investigate the specificity of these astrocytoma-associated antigens.
    • To compare astrocytoma antigen profiles with other cancers.

    Main Methods:

    • Autologous serological typing was performed on cultured astrocytoma cells from 30 patients.
    • Surface antigens were analyzed for their presence on autologous cells, allogeneic tumors, and normal cells.

    Related Experiment Videos

    Main Results:

    • Three distinct classes of surface antigens were defined on astrocytoma cells.
    • Class I antigens were unique to autologous astrocytoma cells.
    • Class II antigens were shared between autologous and some allogeneic tumors but absent in normal cells.
    • Class III antigens were found on both normal and malignant cells, indicating lack of tumor specificity.

    Conclusions:

    • The study successfully classified astrocytoma surface antigens into three distinct groups.
    • The findings suggest potential tumor-specific markers (Class I and II) for astrocytoma.
    • The antigen profile of astrocytoma shares similarities with other malignancies like melanoma and renal carcinoma.