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Related Experiment Videos

Succinylcholine and intraocular pressure

H S Metz, B Venkatesh

    Journal of Pediatric Ophthalmology and Strabismus
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Succinylcholine temporarily increases intraocular pressure in patients undergoing anesthesia. This pressure returns to normal before surgery, suggesting intraocular pressure monitoring may not accurately reflect succinylcholine

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    Area of Science:

    • Ophthalmology
    • Anesthesiology
    • Pharmacology

    Background:

    • Succinylcholine is a common muscle relaxant used before general anesthesia.
    • Its effect on intraocular pressure (IOP) is a concern in ophthalmic surgery.
    • Previous studies suggest a transient rise in IOP following succinylcholine administration.

    Purpose of the Study:

    • To evaluate the effect of succinylcholine on intraocular pressure.
    • To compare the IOP changes induced by succinylcholine versus pancuronium.
    • To assess the reliability of IOP monitoring for evaluating succinylcholine's ocular muscle effects.

    Main Methods:

    • Thirty-one patients received succinylcholine before general anesthesia; IOP was monitored.
    • Ten patients received pancuronium without succinylcholine; IOP was monitored.

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  • Intraocular pressure was measured at baseline and at various intervals post-administration.

    • Main Results:

    • Succinylcholine caused an average IOP rise of 8.2 mm Hg in 61 eyes.
    • Intraocular pressure returned to baseline levels approximately 14 minutes after succinylcholine.
    • Pancuronium did not significantly alter intraocular pressure in 20 eyes.

    Conclusions:

    • Succinylcholine transiently increases intraocular pressure, but it normalizes before surgery begins.
    • Pancuronium does not appear to affect intraocular pressure.
    • Intraocular pressure monitoring may not accurately reflect the duration of succinylcholine's effect on extraocular muscles.