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Updated: Aug 9, 2026

Mouse Models for Graft Arteriosclerosis
Published on: May 14, 2013
Six-year experience with bovine arterial graft for hemodialysis
Insights
Bovine arterial grafts show promising long-term patency in patients requiring multiple angioaccesses. Infection remains a significant cause of graft failure, necessitating careful monitoring.
Area of Science:
- Vascular Surgery
- Biomaterials
- Nephrology
Background:
- Patients requiring frequent hemodialysis often undergo multiple angioaccess procedures.
- Bovine arterial grafts serve as a potential option for vascular access creation.
Purpose of the Study:
- To evaluate the long-term patency and failure modes of bovine arterial grafts used for angioaccess.
- To assess the clinical outcomes of bovine arterial grafts in patients with a history of multiple angioaccesses.
Main Methods:
- Retrospective analysis of 29 bovine arterial grafts implanted in 21 patients over six years.
- Documentation of prior angioaccess procedures, graft patency, patency duration, and reasons for failure.
Main Results:
- Nineteen out of 29 grafts (65.5%) remain patent with a mean patency of 43 months.
- Ten grafts (34.5%) failed, with infection being the primary cause of failure (mean cumulative patency of 46 months).
Conclusions:
- Bovine arterial grafts demonstrate a high patency rate for angioaccess, offering a viable solution for patients with complex vascular needs.
- Infection is a critical complication associated with bovine arterial grafts, highlighting the importance of infection prevention and early detection.
Abstract:
During the last six years 29 bovine arterial grafts were implanted in 21 patients. A total of 186 angioaccesses had been performed on these patients prior to the insertion of bovine graft. Nineteen grafts (65.5%) are still patent with a mean patency time of 43 months. Ten grafts (34.5%) failed, the main cause of failure being infection. The cumulative patency of failed grafts was 46 months.

