Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serum thyroid hormone abnormalities in psychiatric disease

R P Levy, J B Jensen, V G Laus

    Metabolism: Clinical and Experimental
    |November 1, 1981
    PubMed
    Summary

    Euthyroid sick syndrome (ESS), characterized by abnormal thyroid hormone levels in euthyroid patients with nonthyroidal illness, affects 7% of psychiatric admissions initially and up to 27% after hospitalization. Thyroid function tests require cautious interpretation in hospitalized psychiatric patients.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Complications after sentinel node biopsy and inguinal lymph node dissection in penile cancer: a Danish national cohort study.

    International urology and nephrology·2026
    Same author

    Association Between Photodynamic Diagnosis and Risk of Recurrence and Progression in Bacillus Calmette-guérin-treated Nonmuscle Invasive Bladder Cancer Patients: A Nationwide Follow-up Study.

    Urology·2026
    Same author

    ctDNA-guided immunotherapy following radical cystectomy for muscle-invasive bladder cancer: results from the TOMBOLA trial.

    Annals of oncology : official journal of the European Society for Medical Oncology·2026
    Same author

    Unmet informational and supportive care needs of patients with muscle invasive bladder cancer: A systematic review of the evidence.

    European journal of oncology nursing : the official journal of European Oncology Nursing Society·2018
    Same author

    The Convective Transport of Active Species in the Tropics (CONTRAST) Experiment.

    Bulletin of the American Meteorological Society·2018
    Same author

    Genetic Polymorphisms in Organic Cation Transporter 1 Attenuates Hepatic Metformin Exposure in Humans.

    Clinical pharmacology and therapeutics·2017

    Area of Science:

    • Endocrinology
    • Psychiatry

    Background:

    • Euthyroid sick syndrome (ESS) involves abnormal circulating iodothyronine concentrations in euthyroid individuals with nonthyroidal illness (NTI).
    • Psychiatric illness is recognized as a potential cause of ESS.

    Purpose of the Study:

    • To investigate the incidence and characteristics of ESS in psychiatric admissions.
    • To explore the relationship between ESS and psychological attributes in this population.

    Main Methods:

    • A prospective study of 150 consecutive psychiatric admissions.
    • Endocrine and psychological assessments, including serial blood sampling for thyroid hormone levels (T4, T3, FTI, FT3I, TSH).
    • Multivariate statistical analysis to compare psychological attributes between ESS patients and controls.

    Related Experiment Videos

    Main Results:

    • Initial ESS incidence was 7%, rising to 27% with serial sampling, indicating development post-admission.
    • Observed variations in thyroid hormone abnormalities, including elevated T4/FTI, elevated FTI alone, and low T4/FTI.
    • Thyroid hormone abnormalities were mostly transient, with some persistent cases noted.
    • A statistically significant difference (P < .06) in psychological symptoms (somatic and autonomic) was found between ESS patients and controls.

    Conclusions:

    • ESS is as prevalent in psychiatric admissions as in general hospital populations.
    • Thyroid function tests in hospitalized patients, particularly those with psychiatric conditions, should be interpreted with caution due to potential ESS.
    • The findings suggest a link between ESS and specific psychological symptom profiles in psychiatric patients.