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Eye involvement in Kawasaki disease
Journal of Pediatric Ophthalmology and Strabismus
|September 1, 1981
Summary
Kawasaki disease, a childhood illness, can cause eye inflammation (uveitis) during its acute phase. However, follow-up eye exams in children previously diagnosed with Kawasaki disease showed normal results, indicating resolution of ocular symptoms.
Area of Science:
- Pediatrics
- Ophthalmology
- Rheumatology
Background:
- Kawasaki disease (KD) is an acute febrile illness in children.
- KD can lead to severe cardiac complications due to systemic vasculitis.
- Ocular manifestations in KD are not fully understood.
Purpose of the Study:
- To describe the principal signs and symptoms of Kawasaki disease during its acute phase.
- To investigate the prevalence and resolution of anterior uveitis in children with KD.
- To assess long-term ophthalmologic outcomes in patients with a history of KD.
Main Methods:
- Prospective ophthalmologic examinations of 10 children during the acute phase of KD.
- Slit-lamp examinations were performed on 15 patients with a history of KD and conjunctival injection.
- Follow-up evaluations were conducted to assess long-term ocular health.
Main Results:
- Eight out of 10 children exhibited anterior uveitis during the acute phase of KD.
- Ocular inflammation in these cases resolved within two to eight weeks.
- Follow-up examinations of 15 patients with a history of KD revealed normal ophthalmologic findings.
Conclusions:
- Anterior uveitis is a common, transient finding during the acute phase of Kawasaki disease.
- Long-term ophthalmologic sequelae appear uncommon following Kawasaki disease.
- Ophthalmologic evaluation is important for understanding KD's full clinical spectrum.