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[Treatment of Pseudomonas infections in children with cefsulodin (author's transl)]
Wiener Medizinische Wochenschrift (1946)
|October 31, 1981
Insights
Cefsulodin effectively eliminated Pseudomonas aeruginosa in children across various infections, with no observed side effects. This antibiotic showed lasting or temporary eradication in most treated cases.
Area of Science:
- Pediatric Infectious Diseases
- Antimicrobial Therapy
- Bacterial Infections
Context:
- Pseudomonas aeruginosa is a significant pathogen in pediatric infections.
- Diverse pediatric conditions necessitate effective antimicrobial treatments.
- Cefsulodin is an antibiotic investigated for its efficacy against P. aeruginosa.
Purpose:
- To evaluate the effectiveness of Cefsulodin in treating Pseudomonas aeruginosa infections in children.
- To assess the eradication rates and side effects of Cefsulodin therapy.
- To determine the utility of Cefsulodin in various pediatric underlying diseases.
Summary:
- Twenty children with Pseudomonas aeruginosa infections were treated with Cefsulodin.
- Fifty percent of patients received additional antibiotics due to critical need.
- Cefsulodin achieved lasting elimination in 11 cases and temporary elimination in 7 cases.
- No adverse side effects were reported during the treatment period.
Impact:
- Cefsulodin demonstrates significant potential as a treatment option for pediatric Pseudomonas aeruginosa infections.
- The study highlights the safety profile of Cefsulodin in a pediatric population.
- Findings support the use of Cefsulodin in managing various pediatric bacterial infections caused by P. aeruginosa.
Abstract:
Pseudomonas aeruginosa infections of twenty children in various age-groups were treated with Cefsulodin. Fifty percent of these cases received additional other antibiotics due to vital indication. In different underlying diseases such as IRDs, enteritis, omphalitis, necrotizing enterocolitis and urinary tract infection, this treatment achieved in eleven cases a lasting and in seven cases a temporary elimination of pseudomonas aeruginosa. No side effects were seen.