Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recurrent ventricular fibrillation associated with normal QT intervals

T R Shaw

    The Quarterly Journal of Medicine
    |January 1, 1981
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    The influence of urinary pH on the elimination of mexiletine.

    British journal of clinical pharmacology·2012
    Same author

    Influence of the availability of laser transmyocardial revascularisation on surgical strategy in patients with advanced coronary artery disease.

    Cardiology·2001
    Same author

    Significance of commissural calcification on outcome of mitral balloon valvotomy.

    Heart (British Cardiac Society)·2000
    Same author

    Mitral balloon valvotomy for the treatment of mitral stenosis in octogenarians.

    Journal of the American Geriatrics Society·2000
    Same author

    Long term outcome of percutaneous mitral balloon valvotomy in patients aged 70 and over.

    Heart (British Cardiac Society)·2000
    Same author

    Outcome from a rapid-assessment chest pain clinic.

    QJM : monthly journal of the Association of Physicians·1998

    Recurrent syncope due to ventricular fibrillation in two epilepsy patients was linked to a possible forme fruste of long QT syndrome. Propranolol effectively suppressed these cardiac events.

    Area of Science:

    • Cardiology
    • Neurology
    • Genetics

    Background:

    • Epilepsy treatment can span decades, necessitating comprehensive differential diagnoses for recurrent symptoms.
    • Syncope, or fainting, can be caused by various cardiac arrhythmias, including ventricular fibrillation.
    • Long QT syndrome (LQTS) is an inherited cardiac disorder affecting heart rhythm.

    Observation:

    • Two patients with a 20-year epilepsy history presented with recurrent syncope.
    • Electrocardiograms revealed ventricular fibrillation as the cause, despite no structural heart disease.
    • One patient had normal QT/QTc intervals; the second had a normal QT interval with intermittent abnormal U waves.

    Findings:

    • Both patients experienced complete suppression of syncopal attacks with propranolol treatment.

    Related Experiment Videos

  • The clinical presentation suggests a potential forme fruste (subtle form) of long QT syndrome.
  • Absence of overt long QT intervals in these cases challenges typical LQTS diagnostic criteria.

    • Implications:

    • These findings suggest that subtle variants of long QT syndrome may be underdiagnosed in patients with unexplained syncope.
    • Further research into genetic and electrocardiographic markers for forme fruste LQTS is warranted.
    • Considering LQTS in the differential diagnosis for patients with epilepsy and syncope may improve patient outcomes.