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The National Cancer Institute's Natural Products Antineoplastic Development Program
Summary
The National Cancer Institute
Area of Science:
- Natural products chemistry
- Drug discovery
- Oncology
Background:
- The Natural Products Antineoplastic Development Program (NPADP) is a key initiative.
- Natural products have historically yielded significant anticancer agents.
Purpose of the Study:
- To review the current NPADP.
- To discuss novel anticancer agents from natural sources.
Main Methods:
- Review of ongoing research within NPADP.
- Categorization of agents by source: fermentation, plant, and animal.
Main Results:
- Overview of diverse natural product-derived anticancer agents under development.
- Identification of potential candidates from fermentation, plant, and animal sources.
Conclusions:
- The NPADP continues to explore diverse natural product pipelines for new cancer therapies.
- Natural products remain a vital resource for anticancer drug development.