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An improved adhesive patch for long-term collection of sweat
Biomaterials, Medical Devices, and Artificial Organs
|January 1, 1980
Summary
This study introduces an improved adhesive patch for continuous sweat collection over ten days. The reliable sweat collection has potential applications in monitoring drug-taking behavior.
Area of Science:
- Biomedical Engineering
- Analytical Chemistry
Background:
- Continuous physiological monitoring is crucial for understanding health and behavior.
- Existing methods for sweat analysis are often limited in duration and convenience.
Purpose of the Study:
- To develop and evaluate an improved adhesive patch for long-term, continuous sweat collection.
- To assess the feasibility of using the patch for monitoring drug excretion in sweat.
Main Methods:
- Developed an adhesive patch designed for continuous sweat collection.
- Subjects (n=4) wore duplicate patches applied to the skin.
- Collecting pads were weighed every second day over a ten-day period.
- Analyzed sweat uptake linearity and rate.
Main Results:
- The patch demonstrated continuous sweat collection at a steady, linear rate (r2 = 0.99) for up to ten days.
- Uptake rates ranged from 18.38 to 47.01 mg/day (mean = 27.18 mg/day or 0.71 mg/cm2/hour).
- The device proved effective in collecting sweat samples over an extended period.
Conclusions:
- The improved adhesive patch offers a reliable method for continuous sweat collection.
- This technology has significant potential as a non-invasive tool for monitoring drug-taking behavior through sweat analysis.