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Psoriatic arthropathy and crystal-induced synovitis
The Journal of Rheumatology
|March 1, 1980
Summary
Psoriatic arthropathy can occur with both pseudogout and gout simultaneously. Microscopic analysis confirmed calcium pyrophosphate dihydrate and sodium monourate crystals in synovial fluid, revealing crystal topography.
Area of Science:
- Rheumatology
- Crystallography
- Immunology
Background:
- Psoriatic arthropathy is a chronic inflammatory condition.
- Crystalline arthritis includes gout and pseudogout.
- Distinguishing between these conditions is crucial for effective treatment.
Observation:
- Simultaneous presentation of psoriatic arthropathy with pseudogout and gout was observed.
- Synovial fluid analysis was performed on affected joints.
- Leukocytes within the synovial fluid were examined.
Findings:
- Compensating polarizing microscopy unequivocally identified calcium pyrophosphate dihydrate crystals in one case.
- Sodium monourate crystals were identified in another case.
- Surface topography of intracellular sodium monourate crystals was visualized.
Implications:
- This study highlights the possibility of co-existing psoriatic arthropathy and crystalline arthritis.
- Accurate crystal identification is vital for diagnosing and managing complex arthropathies.
- Understanding crystal topography may offer insights into disease mechanisms.