[Effect of Novocaine on the stimulation by lanthanum of intercellular exchange]

Some influences on intercellular junctions permeable to Fluorescein Na were studied with the aid of intracellular glass microelectrodes in the cultures of transformed mouse--embryo kidney cells (MTR) and fibroblast--like cells (L). 1 mM of lanthanum increased the degree of coupling by 2 or 3 times. The preceeding incubation of cells with a 0.02% procaine solution protected them from the influence of lanthanum. A possible mechanism of concurrence between lanthanum and procaine on intercellular junctions is discussed.