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Dysfunctional voiding in children secondary to internal sphincter dyssynergia: treatment with phenoxybenzamine
The Urologic Clinics of North America
|June 1, 1980
Insights
Internal sphincter dyssynergia, a voiding disorder in children, was defined using urodynamic evaluation. Treatment with phenoxybenzamine, an alpha-adrenergic sympatholytic agent, proved successful in resolving this condition.
Area of Science:
- Pediatric Urology
- Urodynamics
- Clinical Medicine
Background:
- Dysfunctional voiding is a common issue in pediatric urology.
- Internal sphincter dyssynergia presents as a clinical challenge in pediatric patients.
- Urodynamic evaluation is crucial for diagnosing voiding disorders.
Purpose of the Study:
- To define and categorize internal sphincter dyssynergia in children.
- To investigate the efficacy of phenoxybenzamine in treating this condition.
Main Methods:
- Urodynamic evaluation was employed to assess bladder and sphincter function.
- Patients diagnosed with internal sphincter dyssynergia were treated with phenoxybenzamine.
- Clinical outcomes were monitored to determine treatment success.
Main Results:
- Internal sphincter dyssynergia was successfully defined and categorized.
- Phenoxybenzamine treatment demonstrated significant success in the studied patient cohort.
- The alpha-adrenergic sympatholytic agent effectively managed the obstructive voiding disorder.
Conclusions:
- Internal sphincter dyssynergia is a distinct clinical entity in pediatric voiding dysfunction.
- Phenoxybenzamine is an effective therapeutic option for children with internal sphincter dyssynergia.
- Urodynamic assessment is vital for accurate diagnosis and management planning.
Abstract:
Through the use of urodynamic evaluation, the authors have been able to define and categorize internal sphincter dyssynergia as a clinical, obstructive, dysfunctional voiding disorder in children. Treatment with the alpha-adrenergic sympatholytic agent, phenoxybenzamine, was successful in their series of patients.