Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Computer simulation of exercise hyperpnea

H Arita, H Yamabayashi

    The Tokai Journal of Experimental and Clinical Medicine
    |April 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Long-term follow-up of collateral pathways established after lymphadenectomy in rats.

    Lymphology·2018
    Same author

    Diagnostic and Prognostic Value of 11C-Methionine PET for Nonenhancing Gliomas.

    AJNR. American journal of neuroradiology·2015
    Same author

    Recurrent mutations of CD79B and MYD88 are the hallmark of primary central nervous system lymphomas.

    Neuropathology and applied neurobiology·2015
    Same author

    Pituitary-Targeted Dynamic Contrast-Enhanced Multisection CT for Detecting MR Imaging-Occult Functional Pituitary Microadenoma.

    AJNR. American journal of neuroradiology·2015
    Same author

    Overexpression of nucleostemin contributes to an advanced malignant phenotype and a poor prognosis in oral squamous cell carcinoma.

    British journal of cancer·2014
    Same author

    Preparation of polymer gel dosimeters based on less toxic monomers and gellan gum.

    Physics in medicine and biology·2013
    Same journal

    Dengue Fever Complicated by Acute Acalculous Cholecystitis and Hemophagocytic Lymphohistiocytosis Despite Negative PCR.

    The Tokai journal of experimental and clinical medicine·2026
    Same journal

    Carbamazepine-Induced Drug-Induced Hypersensitivity Syndrome With Primary Adrenal Insufficiency: A Case Report.

    The Tokai journal of experimental and clinical medicine·2026
    Same journal

    Electrocautery-Assisted Pleural Puncture for a Highly Reproducible Rat Pneumothorax Model.

    The Tokai journal of experimental and clinical medicine·2026
    Same journal

    Effect of a Reduced Frame Rate for Videofluoroscopic Swallowing Studies on the Recognition of Aspiration in Adult Patients.

    The Tokai journal of experimental and clinical medicine·2026
    Same journal

    Successful Engraftment After Repeat Cord Blood Transplantation Using an Identical Conditioning Regimen for MPS II.

    The Tokai journal of experimental and clinical medicine·2026
    Same journal

    Accuracy of Kampo Diagnostic Support System: Comparison With Certified Physicians of the Japan Society for Oriental Medicine.

    The Tokai journal of experimental and clinical medicine·2026
    See all related articles

    A new analog model simulates lung gas exchange and respiratory control to understand exercise hyperpnea. The model supports the combined neurogenic and humoral theory for exercise hyperpnea mechanisms.

    Area of Science:

    • Physiology
    • Respiratory System Modeling
    • Exercise Physiology

    Background:

    • Exercise hyperpnea, the increase in ventilation during exercise, is a complex physiological response.
    • The precise mechanisms controlling exercise hyperpnea, involving both neural and chemical factors, are not fully elucidated.
    • Understanding these mechanisms is crucial for respiratory physiology and clinical applications.

    Purpose of the Study:

    • To develop and validate an analog model simulating lung gas exchange and respiratory control during exercise.
    • To investigate the physiological mechanisms underlying exercise hyperpnea using the developed model.
    • To assess the contribution of neurogenic and humoral factors to respiratory control during exercise.

    Main Methods:

    • Development of a three-compartment analog model (lung, brain, tissue) connected by circulation.

    Related Experiment Videos

  • Inclusion of physiological parameters such as chemoreceptor time delay and time constant.
  • Simulation of respiration controlled by independent and additive neurogenic and humoral factors.

    • Main Results:

    • The model accurately replicated steady-state and transient responses observed during exercise and recovery.
    • Simulated model behavior aligned with experimental data on exercise hyperpnea.
    • The model demonstrated consistency with physiological observations of respiratory adjustments.

    Conclusions:

    • The developed analog model provides a valuable tool for studying exercise hyperpnea.
    • Results support the hypothesis that a combination of humoral and neurogenic control explains exercise hyperpnea.
    • Further research using this model can refine our understanding of respiratory regulation during physical activity.