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Related Experiment Videos

[Case of MD-VD in cattle]

I Simeonov, I Mikhalkov, D Savchev

    Veterinarno-Meditsinski Nauki
    |January 1, 1978
    PubMed
    Summary

    A novel bovine viral diarrhea virus outbreak on a heifer farm caused significant calf mortality. Early fever, respiratory issues, and diarrhea were key clinical signs, with a 28% mortality rate observed in calves.

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    Area of Science:

    • Veterinary Virology
    • Bovine Pathology
    • Infectious Disease Epidemiology

    Context:

    • An enzootic of classic bovine virus diarrhea-mucosal disease (BVD-MD) occurred on a new heifer farm.
    • The disease presented sporadically with intrauterine infections and as an enzootic in calves.

    Purpose:

    • To describe the clinical and pathological features of a BVD-MD outbreak.
    • To isolate and identify the causative virus and demonstrate its antigen.
    • To evaluate treatment efficacy.

    Summary:

    • The enzootic in calves exhibited 100% morbidity and 28% mortality.
    • Clinical signs included fever, respiratory distress, and diarrhea.
    • The causative virus was identified as BVD-MD virus; its antigen was detected via gel precipitation test.
    • Treatment involved a swine fever vaccine (strain K) combined with semiliquid agar, yielding improved outcomes.

    Impact:

    • Provides detailed clinical and pathological data on a significant BVD-MD outbreak.
    • Confirms the etiological agent and demonstrates diagnostic methods.
    • Suggests a potential therapeutic approach for BVD-MD infections.

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