[Preventive effect of several antibiotics in experimental rickettsial infections]

Dibiomycin, biomycin, and biomycin in combination with erythromycin (antibiotics with a wide range of action) used once or in interrupted courses produced a distinct prophylactic effect in experimental rickettsia infection in guinea pigs. The most pronounced prophylactic action was observed when chemoprophylaxis was combined with immunization with inactivated typhud vaccine. Formation of typhus immunity was seen when such chemoprophylaxis scheme was followed.