Angilymphoid hyperplasia appearing as a pilar cyst

Area of Science:

• Dermatopathology
• Vascular Lesions

Background:

• Angiolymphoid hyperplasia with eosinophilia (AHLE) is a benign vascular proliferation.
• Typically presents as multiple subcutaneous nodules.
• Rarely mimics other cutaneous lesions.

Observation:

• A solitary lesion clinically resembling a pilar cyst was observed.
• Histopathological examination revealed angiolymphoid hyperplasia.
• The lesion demonstrated unique intravascular growth within a blood vessel.

Findings:

• This presentation is the first reported solitary case of angiolymphoid hyperplasia.
• Intravascular growth of the lesion is a novel finding.
• The case challenges typical clinical and pathological descriptions of AHLE.

Implications:

• Broadens the differential diagnosis for pilar cyst-like lesions.
• Highlights the importance of thorough histopathological evaluation.
• Contributes to understanding the diverse presentations of angiolymphoid hyperplasia.