Evaluation of the OSM2 hemoximeter

Area of Science:

• Clinical Chemistry
• Medical Instrumentation
• Oximetry

Background:

• Accurate measurement of total haemoglobin concentration ([Hb]) and oxygen saturation (So2) is crucial for patient monitoring.
• The OSM2 oximeter is a device used for these measurements, necessitating an evaluation of its performance.

Purpose of the Study:

• To assess the linearity and repeatability of total haemoglobin ([Hb]) and oxygen saturation (So2) measurements using the OSM2 oximeter.
• To investigate the influence of different haemoglobin variants, specifically carboxyhaemoglobin (HbCO), on oximeter accuracy.

Main Methods:

• Evaluated measurement linearity and repeatability of the OSM2 oximeter for [Hb] and So2.
• Assessed reproducibility of measurements by a single operator and across multiple operators.
• Investigated the effect of foetal haemoglobin and carboxyhaemoglobin on So2 readings.

Main Results:

• Measurements showed good linearity with standard deviations (SD) of 4.2 g/L for [Hb] and 1.08-1.14% for So2.
• Single-operator reproducibility had SDs of 1.1 g/L for [Hb] and 0.32% for So2.
• Inter-operator reproducibility was excellent, with SDs of 0.42 g/L for [Hb] and 0.19% for So2.
• Carboxyhaemoglobin caused a systematic error in So2, enabling HbCO concentration derivation.

Conclusions:

• The OSM2 oximeter demonstrates reliable linearity and repeatability for [Hb] and So2 measurements.
• Inter-operator variability is minimal, indicating robust performance.
• The device can be used to derive carboxyhaemoglobin concentration due to its impact on oxygen saturation readings.