Related Experiment Video
Updated: Aug 14, 2026

08:34
Legionella pneumophila Outer Membrane Vesicles: Isolation and Analysis of Their Pro-inflammatory Potential on Macrophages
Published on: February 22, 2017
[Macrophage migration inhibition reaction in Marseilles fever]
Abstract:
Delayed type hypersensitivity (DTH) was studied in the macrophage migration inhibition test, antibody titers in the CFT and functional activity of spleen macrophages, obtained from guinea-pigs infected with R. conori, in cell cultures. No direct correlation between antibody synthesis and functional macrophage activity accompanied by the development of DTH was revealed. The most pronounced protective function of macrophages could be observed during the decrease of antibody titers and the extinction of DTH.

