Tricuspid atresia with double-outlet left atrium

Area of Science:

• Cardiology
• Developmental Biology
• Pathology

Background:

• Congenital heart defects represent a significant portion of birth defects.
• Understanding rare cardiac malformations is crucial for diagnosis and treatment.

Observation:

• This case presents a rare cardiac malformation with atresia of the right atrioventricular valve.
• The heart exhibited two distinct atrioventricular orifices connecting the left atrium to the left ventricle.
• Additional anomalies included an ostium secundum atrial septal defect and normally related great arteries.

Findings:

• The aorta originated from the main ventricular chamber, while the pulmonary artery arose from the anterior and right-sided outlet chamber.
• The case was characterized by infundibular and valvular pulmonary atresia.
• These findings describe a complex interplay of atrioventricular and outflow tract abnormalities.

Implications:

• This case contributes to the understanding of complex congenital heart disease.
• Detailed pathologic findings can inform surgical planning and prognostic assessment.
• Further research into the embryological basis of such malformations is warranted.