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[Acute normovolemic hemodilution]

B Stanković1, P Romić, T Marenović

  • 1Vojnomedicinska akademija, Institut za transfuziologiju, Beograd.

Medicinski Pregled
|January 1, 1994
PubMed
Summary

Acute normovolemic hemodilution minimizes the need for stored blood transfusions. This technique provides fresh autologous blood and reduces transfusion-related risks in patients undergoing colorectal surgery.

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Area of Science:

  • Anesthesiology
  • Transfusion Medicine
  • Surgical Oncology

Context:

  • Minimizing homologous blood transfusion is crucial in surgery.
  • Transfusion-associated risks include disease transmission and immune modulation.
  • Autologous blood offers immunological advantages over stored homologous blood.

Purpose:

  • To evaluate the efficacy and safety of acute normovolemic hemodilution (ANH) in patients undergoing low rectal resection for colon neoplasms.
  • To assess the reduction in homologous blood transfusion requirements and associated risks.
  • To present initial experiences with ANH in this specific surgical context.

Summary:

  • Twenty patients with low rectal colon neoplasms underwent ANH before low rectal amputation.
  • An average of 780 ml of blood was removed, with simultaneous infusion of crystalloids or colloids.

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  • This ANH protocol aimed to preserve autologous blood and reduce reliance on stored homologous blood, with 15600 ml of autologous and 2500 ml of homologous blood used for transfusion in total.

    • Impact:

    • ANH effectively reduces the need for stored homologous blood transfusions.
    • It mitigates exposure to homologous blood and lowers the incidence of transfusion-transmitted diseases.
    • ANH ensures the availability of fresh, immunologically superior autologous blood and components for transfusion.