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Chemotherapy in osteosarcoma. Basis for application and antagonism to implementation; early controversies surrounding
N Jaffe1, S R Patel, R S Benjamin
1University of Texas Medical School at Houston, USA.
Hematology/Oncology Clinics of North America
|August 1, 1995
Abstract:
Chemotherapy in osteosarcoma has had a major impact in attaining metastasis-free survival, and the cure rates with the use of modern regimens range from 65% to 75%. Preoperative chemotherapy has facilitated surgical resection of the primary tumor, rendering increased numbers of candidates for limb salvage. The effects on the primary tumor may be used as a predictive factor in determining outcome.