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Simultaneous indocyanine green and fluorescein angiography
P M Bischoff1, H J Niederberger, B Török
1Department of Ophthalmology, Kantonsspital, St. Gallen, Switzerland.
Retina (Philadelphia, Pa.)
|January 1, 1995
Summary
Simultaneous indocyanine green (ICG) and fluorescein angiography using a two-wavelength scanning laser ophthalmoscope (SLO) improves choroidal neovascularization (CNV) interpretation in age-related macular degeneration (AMD). This efficient method offers precise dye transit comparison and alignment with retinal landmarks.
Area of Science:
- Ophthalmology
- Medical Imaging
- Retinal Vascular Disease
Background:
- Choroidal dye filling sequence interpretation can be challenging.
- Age-related macular degeneration (AMD) often involves choroidal neovascularization (CNV).
Purpose of the Study:
- To evaluate the utility of simultaneous indocyanine green (ICG) and fluorescein angiography for interpreting choroidal dye filling.
- To assess the feasibility and benefits of a modified two-wavelength scanning laser ophthalmoscope (SLO).
Main Methods:
- A single-wavelength SLO was adapted into a two-wavelength system for simultaneous ICG and fluorescein angiography.
- The technique was applied to 340 patients, many with AMD and CNV.
Main Results:
- Simultaneous ICG and fluorescein angiography is feasible with high-quality imaging.
- Combined red-green images can be generated from corresponding ICG and fluorescein angiograms.
Conclusions:
- This method allows precise comparison of dye transit times and alignment of ICG angiograms with fluorescein landmarks.
- It offers significant time efficiency with a single injection and photographic session.