Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Oral leukoplakia

J J Sciubba1

  • 1Department of Dental Medicine, Long Island Jewish Medical Center, New Hyde Park, New York 11040, USA.

Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Immunoprofile of the adenomatoid odontogenic tumor.

Oral diseases·2016
Same author

End-of-life care in the head and neck cancer patient.

Oral diseases·2016
Same author

Neuralgia-inducing cavitational osteonecrosis: a status report.

Oral diseases·2009
Same author

Oral precancer and cancer: etiology, clinical presentation, diagnosis, and management.

Compendium of continuing education in dentistry (Jamesburg, N.J. : 1995)·2002
Same author

Oral cancer and its detection. History-taking and the diagnostic phase of management.

Journal of the American Dental Association (1939)·2002
Same author

Oral cancer. The importance of early diagnosis and treatment.

American journal of clinical dermatology·2001
Same journal

Oral health, atherosclerosis, and cardiovascular disease.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists·2004
Same journal

The use of enamel matrix derivative in the treatment of periodontal defects: a literature review and meta-analysis.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists·2004
Same journal

Pathogenesis of apical periodontitis and the causes of endodontic failures.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists·2004
Same journal

The role of TGF-beta in epithelial malignancy and its relevance to the pathogenesis of oral cancer (part II).

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists·2004
Same journal

TGF-beta signal transduction in oro-facial health and non-malignant disease (part I).

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists·2004
Same journal

Virulence factors of Enterococcus faecalis: relationship to endodontic disease.

Critical reviews in oral biology and medicine : an official publication of the American Association of Oral Biologists·2004
See all related articles

Leukoplakia, a clinical condition, involves cellular atypia and dysplasia. Understanding its causes, like tobacco and Candida albicans, and its varied management is key for oral health.

Area of Science:

  • Oral pathology
  • Oncology
  • Dermatology

Background:

  • Leukoplakia is a recognized clinico-pathologic concept with a worldwide clinical designation.
  • Understanding its biology involves cellular atypia and epithelial dysplasia.
  • Clinical subsets, like verrucous leukoplakia, indicate varied behavior patterns.

Purpose of the Study:

  • To review the evolving understanding of leukoplakia.
  • To discuss the etiologic factors and potential role in carcinogenesis.
  • To outline current management strategies.

Main Methods:

  • Literature review of leukoplakia's clinico-pathologic evolution.
  • Analysis of etiologic factors including tobacco, Candida albicans, and viruses.
  • Investigation of genetic alterations and management approaches.

Related Experiment Videos

Main Results:

  • Tobacco remains a primary etiologic factor, but other factors are considered.
  • Candida albicans and viruses like Epstein-Barr virus and human papilloma virus are implicated.
  • Genetic alterations, such as p53 mutations, are under investigation.

Conclusions:

  • Leukoplakia management is variable, encompassing local, topical, and systemic therapies.
  • Antioxidants, carotenoids, and retinoids are among the systemic treatment options.
  • Further research into etiologies and targeted therapies is warranted.