Related Experiment Video
Updated: Aug 7, 2026

A Mouse Model of Intestinal Partial Obstruction
Published on: March 5, 2018
[Amyloid intestinal pseudo-obstruction as initial manifestation of IgA multiple myeloma]
P Domingo-García1, J L Pardo-García, M Martínez-Albaladejo
1Servicio de Cirugía, Hospital Comarcal del Noroeste, Caravaca de la Cruz, Murcia.
Abstract:
Amyloidosis is a well known complication of Multiple Myeloma. Although involvement of the gastrointestinal tract is common in patients with Amyloid, severe symptoms are no frequent, nevertheless vascular deposits may produce gastrointestinal ischemia and bleeding and perforation. Injured mucosae of the intestinal well may produce malabsorption and the neuromuscular infiltration determine alterations of gastrointestinal motility. Although renal and cardiac disfunction is the most frequently cause of death in these patients, intestinal pseudo-obstruction bears a serious prognosis. We present a case of a patients who was operated because of a presumptive diagnosis of intestinal obstruction, which small bowel was infiltrated with Amyloid and which bone marrow demonstrated multiple myeloma.
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