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Related Experiment Videos

The poisoned patient. Toxicologic emergencies

L H Norris1, M B Papageorge

  • 1Department of Oral and Maxillofacial Surgery, Tufts University School of Dental Medicine, Boston, Massachusetts, USA.

Dental Clinics of North America
|July 1, 1995
PubMed
Summary

Dentists routinely use various medications, but their safe therapeutic ranges can lead to ignored adverse reactions. This review covers toxicity, allergies, drug interactions, and the impact of alcohol and recreational drugs in dental practice.

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Area of Science:

  • Pharmacology
  • Dental Medicine
  • Toxicology

Background:

  • Common dental medications include local anesthetics, analgesics, antibiotics, and antianxiety agents.
  • These drugs are routinely administered in dental settings.
  • Therapeutic dose ranges for most dental agents are wide, potentially leading to underestimation of adverse reaction risks.

Purpose of the Study:

  • To review potential adverse drug reactions in dentistry.
  • To discuss toxicity, allergy, and idiosyncrasy related to dental medications.
  • To examine drug interactions and the influence of alcohol and recreational drugs on dental treatment.

Main Methods:

  • Literature review of adverse drug events in dental practice.
  • Discussion of pharmacological principles related to common dental agents.

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  • Analysis of case reports and clinical guidelines concerning drug safety.
  • Main Results:

    • Adverse reactions can stem from toxicity, allergic responses, or idiosyncratic drug reactions.
    • Potential exists for significant drug interactions with commonly prescribed dental medications.
    • Concurrent use of alcohol or recreational drugs can exacerbate risks associated with dental treatments.

    Conclusions:

    • Awareness of potential adverse reactions is crucial for safe dental practice.
    • Careful patient history regarding medications, alcohol, and recreational drug use is essential.
    • Understanding drug interactions and individual patient responses improves patient safety.